A drug dissolution test is one of the most critical and important tests used for developing and evaluating tablet/capsule products. However, unfortunately, as conducted at present the test is also perhaps one of the most frustrating and the least value adding tests one would use. The test is often promoted as a quality control test or tool as well, however, without defining or linking to a quality parameter/end-point. It is conducted using apparatuses which have never been validated for the intended purpose or objective, which further adds to the frustration. This article describes reasons for such practices and frustrations, and suggests a simple approach to address the issues and concerns.
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